Wait for Botwoon to spawn then use a Plasma Special Beam Attack. Use XRay to slow time and watch for a particle to overlap Botwoons head, then proceed to Microwave.

Requires:

{
  "notable": "Back-Side Plasma Shield Microwave"
}
"h_navigateUnderwater"
"canSpecialBeamAttack"
"Plasma"
"canXRayWaitForIFrames"
{
  "ammo": {
    "type": "PowerBomb",
    "count": 1
  }
}
{
  "or": [
    "canTrickyDodgeEnemies",
    {
      "ammo": {
        "type": "PowerBomb",
        "count": 2
      }
    }
  ]
}
{
  "or": [
    "canBeLucky",
    {
      "ammo": {
        "type": "PowerBomb",
        "count": 1
      }
    }
  ]
}

Clears obstacles: f_DefeatedBotwoon

Sets flags: f_DefeatedBotwoon

Dev note: Killing in 1 SBA takes some luck. Microwaving effeciently takes some dexterity. This strat only applies to those who don't know the magic pixel strat is possible.